The Lady Cougars broke a 44-game losing streak that dated back to Feb. 2, 2012, on Tuesday, beating Webber, 50-45.
South Central exploded for 20 points in the fourth quarter to help overcome its eight-point halftime deficit.
Freshman Abby Hahn led the team with 15 points and freshman Autumn McCoy set her career-high, with 11.
The Lady Cougars (1-18) hadn’t won since beating Wayne City, 47-43, in 2012. Jenna Rose and Bailey Ritter are the only players on the team to have played in both games.